Most of the substrates are provided in a lyophilized/dried form, stored under protective gas, which enables NanoLight to ship them at room temperature, a major advantage for the increasing challenges in international shipments.
Since 2012 NanoLight has been providing non-toxic, water-soluble bioluminescent substrates mainly for the field of in vivo imaging to monitor tumor growth in mouse models. Another very recent application is the field of Optogenetics that gives neuroscientists the incredible ability to control neurons using bioluminescence.
Our research team continues to expand the product portfolio. Our recent discoveries like “Prolume Purple™” (patent US 9,624,425), is a novel substrate that outperforms DeepBlueC™, a widely popular substrate to study protein-protein interaction.
In addition to basic bioluminescent compounds, NanoLight is incorporating these substrates into complex buffer systems for a variety of luciferases with different kinetic profiles, providing convenience to researches, as well as reliable batch-controlled reagents for automated high-throughput screenings by pharmaceutical companies.
NanoLight is also a leader in developing tools for sensing molecular targets. We offer Streptavidin-conjugation for the world’s two brightest luciferases known so far:
Gaussia (GLuc-SA) and Oplophorous (NLuc-SA) luciferases, enabling easy detection of biotinylated molecules (like DNA, RNA, peptides, proteins).
Utilizing decades of experience in the bioluminescent field, NanoLight is offering custom reagents for specific and complex applications that would be largely ignored by other companies in the field. We work closely with customers in research institutes and universities, which enables us to identify trends and provide products and services accordingly.